Abstract
Alcohol Use Disorder or alcoholism is a chronic physical and psychological condition that represents one of the main causes of global deterioration and mortality. Conventional interventions reveal access barriers; therefore, the inclusion of a technological resource is an alternative to improve the effectiveness and adherence to treatments. To analyze the effectiveness of technological interventions reported in the scientific literature for alcoholism. A systematic review with a qualitative and descriptive approach was carried out using the Rayyan tool and the PRISMA method for the screening, classification, and refinement of articles. The Scopus and PubMed databases were used, with MeSH and DeCS terms, boolean operators, and keywords. The CASPe critical appraisal checklists were applied to assess methodological quality. Information from six randomized clinical trials and one cohort study was selected, four of which reported higher methodological quality. The identified mobile applications included SLB, ALCO-VR, TMC, ACHESS, and SoberDiary. The digital version of Cognitive Behavioral Therapy (CBT) was implemented through the CBT4CBT program, and Cue Exposure Therapy was applied using virtual reality. No substantial differences were reported between conventional treatment and the implementation of technology for alcoholism. Most studies demonstrated technological resources supported by traditional CBT to improve treatment effectiveness and adherence among individuals with alcoholism; this was the foundation of their effectiveness, although no superiority in their use was indicated.
References
Abraira, V., Muirel, A., & Montes, M. (2022). Lectura crítica de estudios de pronóstico. Estudios de cohortes. En J. B. Cabello, (ed.). Lectura crítica de la evidencia clínica (pp. 67–77). Elsevier.
American Psychiatric Association. (2014). Manual diagnóstico y estadístico de los trastornos mentales DSM-5. Editorial Médica Panamericana.
Barnett, N. P., Meade, E. B., & Glynn, T. R. (2014). Predictors of detection of alcohol use episodes using a transdermal alcohol sensor. Experimental and Clinical Psychopharmacology, 22(1), 86–96. https://doi.org/10.1037/a0034821
Biswal, B., Bora, S., Anand, R., Bhatia, U., Fernandes, A., Joshi, M., & Nadkarni, A. (2024). A systematic review of interventions to enhance initiation of and adherence to treatment for alcohol use disorders. Drug and Alcohol Dependence, 263. https://doi.org/10.1016/j.drugalcdep.2024.112429
Cabello, J. B., López, E., & Pijoan, J. L. (2022). Lectura crítica de estudios de tratamiento. Ensayos clínicos aleatorios. En J. B. Cabello, (ed.). Lectura crítica de la evidencia clínica (pp. 36–56). Elsevier.
Chen, J., Qian, M., Sun, C., Lin, M., & Tang, W. (2019). Clinical effectiveness of cognitive behavioural therapy on alcohol-dependent patients: An observation with the WeChat platform. General Psychiatry, 32(4). https://doi.org/10.1136/gpsych-2019-100087
Gamito, P., Oliveira, J., Matias, M., Cunha, E., Brito, R., Lopes, P. F., & Deus, A. (2021). Virtual reality cognitive training among individuals with alcohol use disorder undergoing residential treatment: Pilot randomized controlled trial. Journal of Medical Internet Research, 23(1). https://doi.org/10.2196/18482
Hernández-Serrano, O., Ghi??, A., Fernández-Ruiz, J., Monràs, M., Gual, A., Gacto, M., Porras-García, B., Ferrer-García, M., & Gutiérrez-Maldonado, J. (2021). Determinants of cue-elicited alcohol craving and perceived realism in virtual reality environments among patients with alcohol use disorder. Journal of Clinical Medicine, 10(11). https://doi.org/10.3390/jcm10112241
Ingersoll, K., Frederick, C., MacDonnell, K., Ritterband, L., Lord, H., Jones, B., & Truwit, L. (2018). A pilot RCT of an internet intervention to reduce the risk of alcohol-exposed pregnancy. Alcoholism: Clinical and Experimental Research, 42(6), 1132–1144. https://doi.org/10.1111/acer.13635
Johansson, M., Romero, D., Jakobson, M., Heinemans, N., & Lindner, P. (2024). Digital interventions targeting excessive substance use and substance use disorders: A comprehensive and systematic scoping review and bibliometric analysis. Frontiers in Psychiatry, 15. https://doi.org/10.3389/fpsyt.2024.1233888
Johansson, M., Sinadinovic, K., Gajecki, M., Lindner, P., Berman, A. H., Hermansson, U., & Andréasson, S. (2021). Internet-based therapy versus face-to-face therapy for alcohol use disorder, a randomized controlled non-inferiority trial. Addiction, 116(5), 1088–1100. https://doi.org/10.1111/add.15270
Khatore, P., Yolanda, H., Joyner, J., & Nadkarni, A. (2025). Digital interventions for alcohol use and alcohol use disorders in low- and-middle-income countries: A systematic review. Oxford Open Digital Health, 3(1). https://doi.org/10.1093/oodh/oqaf004
Kiluk, B. D., Benitez, B., DeVito, E. E., Frankforter, T. L., LaPaglia, D. M., O’Malley, S. S., & Nich, C. (2024). A digital cognitive behavioral therapy program for adults with alcohol use disorder: A randomized clinical trial. JAMA Network Open, 7(9). https://doi.org/10.1001/jamanetworkopen.2024.35205
Kwan, I., Burchett, H. E. D., Macdowall, W., D’Souza, P., Stansfield, C., Kneale, D., & Sutcliffe, K. (2025). How effective are remote and/or digital interventions as part of alcohol and drug treatment and recovery support? A systematic review and meta-analysis. Addiction, 120(8), 1531–1550. https://doi.org/10.1111/add.70021
Liu, S.-W., You, C.-W., Fang, S.-C., Chang, H.-M., & Huang, M.-C. (2023). A smartphone-based support system coupled with a bluetooth breathalyzer in the treatment of alcohol dependence: A 12-week randomized controlled trial. Internet Interventions, 33. https://doi.org/10.1016/j.invent.2023.100639
McKay, J. R., Gustafson, D. H., Ivey, M., Pe-Romashko, K., Curtis, B., Thomas, T., Oslin, D. W., Polsky, D., Quanbeck, A., & Lynch, K. G. (2022). Efficacy and comparative effectiveness of telephone and smartphone remote continuing care interventions for alcohol use disorder: A randomized controlled trial. Addiction, 117(5), 1326–1337. https://doi.org/10.1111/add.15771
Mekonen, T., Chan, G. C. K., Connor, J., Hall, W., Hides, L., & Leung, J. (2021). Treatment rates for alcohol use disorders: A systematic review and meta-analysis. Addiction, 116(10), 2617–2634. https://doi.org/10.1111/add.15357
Mellentin, A. I., Nielsen, B., Nielsen, A. S., Yu, F., Mejldal, A., Nielsen, D. G., & Stenager, E. (2019). A mobile phone app featuring cue exposure therapy as aftercare for alcohol use disorders: An investigator-blinded randomized controlled trial. JMIR mHealth and uHealth, 7(8). https://doi.org/10.2196/13793
Ndulue, O. I., & Naslund, J. A. (2024). Digital interventions for alcohol use disorders: A narrative review of opportunities to advance prevention, treatment and recovery. Psychiatry Research Communications, 4(3). https://doi.org/10.1016/j.psycom.2024.100183
Organización Mundial de la Salud. (2024, 25 de junio). Alcohol. https://www.who.int/es/news-room/fact-sheets/detail/alcohol
Ouzzani, M., Hammady, H., Fedorowicz, Z., & Elmagarmid, A. (2016). Rayyan: A web and mobile app for systematic reviews. Systematic Reviews, 5(1), 210. https://doi.org/10.1186/s13643-016-0384-4
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., … & Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372(71). https://doi.org/10.1136/bmj.n71
Tait, R. J., Paz Castro, R., Kirkman, J. J. L., Moore, J. C., & Schaub, M. P. (2019). A digital intervention addressing alcohol use problems (the “Daybreak” program): Quasi-experimental randomized controlled trial. Journal of Medical Internet Research, 21(9). https://doi.org/10.2196/14967
Tarp, K., Christiansen, R., Bilberg, R., Borkner, S., Dalsgaard, C., Paldam Folker, M., & Søgaard Nielsen, A. (2024). Patient perspectives on blended internet-based and face-to-face cognitive behavioral therapy for alcohol use disorder: Qualitative study. Journal of Medical Internet Research, 26. https://doi.org/10.2196/47083
Tarqui-Silva, L. E., Vinicio, M., & Salinas, S. (2024). Tratamientos residenciales para adicciones en Ecuador: el limbo entre la bioética y los derechos humanos. Universidad y Sociedad, 16(1), 89–95.

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